Profile of Thyroid Cancer at Dr. Kariadi General Hospital Semarang in 2020

Alif Muhammad Sudarmanto, Yan Wisnu Prajoko, Hermawan Istiadi, Eka Yudhanto


Background: Thyroid cancer is ranked ninth among the most common type originating from the endocrine glands globally, accounting for approximately 59.7% of cases in Asia. According to 2020 health data, thyroid cancer ranked twelfth in Indonesia, comprising 13,114 cases. Despite the number of cases recorded, there is a lack of comprehensive data regarding the condition of thyroid cancer in the country. Therefore, this research aimed to describe the thyroid cancer profile in Dr. Kariadi General Hospital Semarang.

Methods: This descriptive research was carried out using 154 medical records selected through consecutive sampling from Dr. Kariadi General Hospital Semarang from January to December 2020. Categorical scale data were described through frequencies and percentages, while numerical scale data were presented as mean and standard deviation.

Results: This research discovered that 57.8% of patients belonged to the 40–59-year-old age group, predominantly consisting of 79.9% females. Additionally, 39.6% of patients had normal thyroid function, with Papillary Thyroid Cancer being the most common type, constituting 92.7% of cases. The results showed that 46.8% of cases were bilateral, 37.7% had a condition of T3, 59.7% had N0, and 89.6% had M0, while 66.2% were classified as stage I.

Conclusions: The majority of thyroid cancer patients were 45–64 years old and female. The results showed Papillary Thyroid Cancer as the most prevalent type, with the majority of cases diagnosed at stage I and showing bilaterally presentation. Most of the data correlated with previous research, except thyroid function and histopathology-type percentages.


profile, statistics, thyroid cancer

Full Text: View | Download

DOI: 10.33371/ijoc.v18i1.1017

Article Metrics

Abstract View: 84,
PDF Download: 28


Setiati S, Simadibrata KM, Alwi I, Setiyohadi B, Sudoyo AW. Buku Ajar Ilmu Penyakit Dalam Jilid: 2. 6th ed. Jakarta: Interna Publishing; 2014.

Global Cancer Observatory. Thyroid Fact Sheet [Internet]. 2020. Available from:

Global Cancer Observatory. Indonesia Fact Sheet [Internet]. 2020. Available from:

Global Cancer Observatory. Estimated number of new cases from 2020 to 2040, Incidence, Both sexes, age [0-85+]: Thyroid [Internet]. 2020 [cited 2021 Jan 23]. Available from:

Prajoko YW. Profil Penderita Karsinoma Tiroid di RSUP dr. Kariadi, Semarang (Januari 2006 Juni 2010). Indones J Cancer. 2013;7(4).

World Health Organization. WHO report on cancer: setting priorities, investing wisely and providing care for all. Geneva: World Health Organization; 2020. 149 p.

Badan Penelitian dan Pengembangan Kesehatan. Laporan Nasional Riskesdas 2018. Jakarta: Lembaga Penerbit Badan Penelitian dan Pengembangan Kesehatan; 2018. 628 p.

Pusat Data dan Informasi Kementerian Kesehatan RI. Beban Kanker di Indonesia. InfoDatin Pusat Data dan Informasi Kementerian Kesehatan RI. 2019;

Ito Y, Miyauchi A, Kihara M, et al. Patient Age Is Significantly Related to the Progression of Papillary Microcarcinoma of the Thyroid Under Observation. Thyroid. 2013 Sep 3;24(1):27–34.

Kitahara CM, Sosa JA. The changing incidence of thyroid cancer. Nat Rev Endocrinol. 2016;12(11):646–53.

Liu Y, Su L, Xiao H. Review of Factors Related to the Thyroid Cancer Epidemic. Int J Endocrinol. 2017;2017:5308635

Gonzalez-Gonzalez R, Bologna-Molina R, Carreon-Burciaga RG, et al. Papillary Thyroid Carcinoma: Differential Diagnosis and Prognostic Values of Its Different Variants: Review of the Literature. Wolfson AH, Piazza C, editors. ISRN Oncol. 2011;2011:915925.

Girardi FM, Barra MB, Zettler CG. Variants of papillary thyroid carcinoma: association with histopathological prognostic factors. Braz J Otorhinolaryngol. 2013;79(6):738–44.

Kaliszewski K, Zubkiewicz-Kucharska A, Kiełb P, et al. Comparison of the prevalence of incidental and non-incidental papillary thyroid microcarcinoma during 2008–2016: a single-center experience. World J Surg Oncol. 2018;16(1):202.

Romero-Rojas A, Cuervo-Martínez J, Osorio-Arango K, Olaya N. Variantes histológicas y factores pronósticos del carcinoma papilar de tiroides en el Instituto Nacional de Cancerología de Colombia, 2006-2012. Biomédica. 2015 May 13;35(3).

Grani G, Lamartina L, Durante C, et al. Follicular thyroid cancer and Hürthle cell carcinoma: challenges in diagnosis, treatment, and clinical management. Lancet Diabetes Endocrinol. 2018;6(6):500–14.

Cabanillas ME, McFadden DG, Durante C. Thyroid cancer. Lancet. 2016;388(10061):2783–95.

Tuttle RM, Haugen B, Perrier ND. Updated American Joint Committee on Cancer/Tumor-Node-Metastasis Staging System for Differentiated and Anaplastic Thyroid Cancer (Eighth Edition): What Changed and Why? Thyroid. 2017 Jun;27(6):751–6.

Ibrahim MIS, Jusoh YR, Adam NN, Mohamad I. Primary Squamous Cell Carcinoma of the Thyroid Gland. Iran J Otorhinolaryngol. 2018 Jan;30(96):65–8.

Lam AK. Squamous cell carcinoma of thyroid: a unique type of cancer in World Health Organization Classification. Endocr Relat Cancer. 2020;27(6):R177–92.

Chernock RD, Rivera B, Borrelli N, et al. Poorly differentiated thyroid carcinoma of childhood and adolescence: a distinct entity characterized by DICER1 mutations. Mod Pathol. 2020 Jul;33(7):1264–74.


  • There are currently no refbacks.

Copyright (c) 2024 Indonesian Journal of Cancer

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.