Transcatheter Arterial Chemo Infusion (TACI) for Squamous Cell Carcinoma of the Tongue: A Case Report
Abstract
Introduction: Cancers of the lip and oral cavity, with the tongue being the most common site, accounted for more than 377,700 cases and more than 177,700 deaths worldwide in 2020. Ninety percent of these oral neoplasms are squamous cell carcinomas (SCC). The main treatments for oral cancers are surgery, radiotherapy, and chemotherapy, either combined or as stand-alone therapies. Transcatheter Arterial Chemo Infusion (TACI) is considered the definitive treatment for locoregionally advanced squamous cell carcinoma of the oral cavity, aiming to preserve function after surgery while maintaining or improving locoregional control and survival rates. This case report presents the qualitative result of TACI on SCC of the tongue. The aim of this case report is to demonstrate the potency of TACI as an alternative palliative therapy for SCC of the tongue.
Case Presentation: A 37-year-old man with SCC of the tongue was diagnosed and treated at Dr. Sardjito General Hospital, Yogyakarta in 2021. The patient underwent TACI procedure and subsequent radiotherapy sessions subsequently. The therapeutic response was evaluated by observing the clinical morphology of the lesions.
Conclusions: TACI is a minimally invasive technique used in the management of SCC. TACI has shown its potency as an efficient and effective alternative palliative therapy.
Keywords
DOI: 10.33371/ijoc.v18i2.1043
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References
Ang KK, Harris J, Wheeler R, et al. Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med. 2010 Jul 1;363(1):24-35.
Rivera C. Essentials of oral cancer. Int J Clin Exp Pathol. 2015;8(9):11884–94.
National Cancer Institute. Bethesda, MD [Internet]. [cited 2022 Jun 7]. SEER Cancer Stat Facts: Tongue Cancer. Available from: https://seer.cancer.gov/statfacts/html/tongue.html
Tohnai I. Chemotherapy using intra-arterial infusion for oral cancer. Nagoya J Med Sci. 2006;68(3–4):101–8.
Shinlapawittayatorn K, Chattipakorn SC, Chattipakorn N. The effects of doxorubicin on cardiac calcium homeostasis and contractile function. J Cardiol. 2022;80(2):P125-132.
Ma MC, Chen YY, Li SH, et al. Intra-arterial chemotherapy with doxorubicin and cisplatin is effective for advanced hepatocellular cell carcinoma. Sci World J. 2014;2014.
Oya R, Takagi S, Inenaga R, et al. Targeted Intra-Arterial Carboplatin Chemoradiotherapy and Tegafur/Uracil for Oral and Oropharyngeal Cancer. J UOEH. 2006;28(4):381–94.
Fuwa N, Kodaira T, Furutani K, et al. Treatment results of continuous intra-arterial CBDCA infusion chemotherapy in combination with radiation therapy for locally advanced tongue cancer. Oral Surgery, Oral Med Oral Pathol Oral Radiol Endodontology. 2008 Jun;105(6):714–9.
Woo S Bin. Oral Epithelial Dysplasia and Premalignancy. Head Neck Pathol. 2019;13(3):423–39.
Huang Y, Lan Y, Zhang Z, et al. An Update on the Immunotherapy for Oropharyngeal Squamous Cell Carcinoma. Front Oncol. 2022;12(March):1–10.
Caponigro F, Ionna F, Scarpati GDV, et al. Translational Research: A Future Strategy for Managing Squamous Cell Carcinoma of the Head and Neck? Anti Cancer Agents Med Chem. 2018;18(9):1220–7.
Perri F, Longo F, Caponigro F, et al. Management of HPV-Related Squamous Cell Carcinoma of the Head and Neck: Pitfalls and Caveat. Cancers (Basel). 2020 Apr 15;12(4):975.
Kato MG, Baek C, Chaturvedi P, et al. Update on oral and oropharyngeal cancer staging – International perspectives. World J Otorhinolaryngol - Head Neck Surg. 2020;6(1):66–75.
Gonzales M, March AR. Tongue Cancer. Treasure Island (FL): StatPearls Publishing. 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK562324
Oikawa Y, Kugimoto T, Kashima Y, et al. Surgical treatment for oral tongue squamous cell carcinoma: A retrospective study of 432 patients. Glob Heal Med. 2021;3(3):157–62.
Sun MH, Yi WD, Shen L, et al. Transcatheter arterial infusion chemotherapy and embolization for primary lacrimal sac squamous cell carcinoma: A case report. World J Clin Cases. 2022 Jul 26;10(21):7467-7473.
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