Schwannoma in Hemophilic Patient: Surgical Considerations
Introduction: Schwannoma is a benign, encapsulated, tumor that arises from Schwann cells of myelinated nerves. In this report, we present a case of schwannoma in a hemophilic patient and its surgical considerations related to bleeding complications.
Case Presentation: We present a case of a 27-year-old male coming to our center with a chief complaint of a painless, non-progressive growing mass on the back of his head since a year prior to admission. Physical examination showed that the mass was mobile, firm, and had a welldefined margin beneath the scalp. His radiograph showed a soft tissue mass beneath the scalp. MRI demonstrated a dense-multilobulated mass without intracranial infiltration. The patient had hemophilia A from the age of 5. We performed marginal excision of the mass with regiments of factor VIII (FVIII) concentrates preoperatively, intraoperatively, and postoperatively. Pathology was consistent with schwannoma.
Conclusions: Schwannoma management in hemophilic patients needs several considerations. Perioperative planning plays a major part in the management of patients with tumors and hemophilia to prevent bleeding complications.
Anderson CL, Alvarez O, Saigal G, et al. Hemophilic pseudotumor: An important differential diagnosis of an intracranial mass. J Pediatr Hematol Oncol. 2015;37:219–22.
Chandran Nair S, Viswabandya A, Srivastava A. Diagnosis and management of von Willebrand Disease: A developing country perspective. Semin Thromb Hemost. 2011;37: 587–94.
Hilton DA, Hanemann CO. Schwannomas and their pathogenesis. Brain Pathol. 2014;24: 205–20.
Mankin HJ, Mankin KP. Schwannoma: A rare benign tumor of soft tissues. Musculoskelet Surg. 2014;98:95–9.
Kamal AF, Pradana AS, Prabowo Y. Bilateral iliopsoas haemophilic ‘soft tissue pseudotumours’: A case report. Int J Surg Case Rep. 2015;13:19–23.
International Agency for Research on Cancer. WHO Classification of Tumours of Soft Tissue and Bone. 4th edition. Lyon: World Health Organization, 2013.
Majbar A, Hrora A, Jahid A, et al. Perineal schwannoma. BMC Res Notes. 2016;9:1–3.
Ghosh BC, Ghosh L, Huvos AG, et al. Malignant schwannoma. A Clinicopathologic Study. Cancer. 1973;31:184–90.
Kamal AF, Sukrisman L, Dilogo IH, et al. Pelvic haemophilic pseudotumour: A case report. J Orthop Surg. 2014;22:263–8.
Cohen MS, Chen NC. Total elbow arthroplasty. In: Wolfe SW, Hotchkiss RN, Pederson WC, Kozin SH, Cohen MS, eds. Green's Operative Hand Surgery. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 27.
Okamoto A, Yamamoto K, Eguchi G, et al. Perioperative management of hemophilia a using recombinant factor VIII in patients undergoing major or minor surgery. Blood. 2018;132:5082–5082.
Viswabandya A, Mathews V, George B, et al. Successful surgical haemostasis in patients with von Willebrand disease with Koate®DVI. Haemophilia. 2008;14:763–7.
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