Magnetic Resonance Findings in Adolescent Vaginal Rhabdomyosarcoma: A Rare Case Report

Trifonia Pingkan, Fitri Juniarta, Hartono Tjahjadi, Meliyana Lai

Abstract


Introduction: Rhabdomyosarcoma (RMS) is a rare soft tissue tumor, mainly affecting children, adolescents, and adults younger than 15 years, representing 3% to 4% of all childhood malignancies. Genitourinary is the second-most-common location of RMS with around 25% of cases. We describe a rare case of vaginal rhabdomyosarcoma in adolescents with huge polypoid tumors.

 

Case Presentation: A 15-year-old female presented with vaginal bleeding for seven months. Her medical story was unremarkable. The clinical examination showed a polypoid mass prolapsed from the vagina, and the laboratory result was anemia. The pelvic magnetic resonance imaging (MRI) showed a heterogenous bulky solid tumor in the vagina. The histopathological finding revealed a sarcoma, and the immunohistochemical staining result was rhabdomyosarcoma not otherwise specified (NOS).

 

Conclusions: Vaginal RMS is a rare malignant tumor of mesenchymal origin with skeletal muscle differentiation. Vaginal RMS is the most common site of genitourinary RMS and presents as a rapidly growing and aggressive local mass. Imaging plays an important role in the initial diagnosis of vaginal RMS, regarding the presentation of the bulky protruding tumor on the vaginal region


Keywords


magnetic resonance imaging, rhabdomyosarcoma, vagina

References


Yang J, Yang J, Yu M, et al. Clinical Study on Female Genital Tract Rhabdomyosarcoma in Childhood: Changes During 20 Years in One Center. Int J Gynecol Cancer. 2017;27(2):311-4.

Chauhan RS, Singh DK, Guha B, et al. Multimodality imaging of vaginal rhabdomyosarcoma. Indian J Radiol Imaging. 2017;27:148–51.

Habib MA, Shamsuzzaman M, Khanum JA, et al. Vaginal rhabdomyosarcoma in an infant: a case report. Dinajpur Med Col J. 2015;8:243-5.

Egas-Bejar D, Huh WW. Rhabdomyosarcoma in adolescent and young adult patients: current perspectives. Adolesc Health Med Ther. 2014;5:115-25.

Rudzinski ER, Anderson JR, Hawkins DS, et al. The World Health Organization classification of skeletal muscle tumor in pediatric rhabdomyosarcoma: a report from the Children’s Oncology Group. Arch Pathol Lab Med. 2015;139:1281-7.

Lalya I, Laatitioui S, Essadi I, et al. Vaginal embryonal rhabdomyosarcoma in young woman: A case report and literature review. Arch Cancer Sci Ther. 2020;4:34-7.


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DOI: 10.33371/ijoc.v16i1.842

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