The Profile of Soft Tissue Sarcoma Patients who Undergo Radiotherapy in Dr. Hasan Sadikin General Hospital Bandung
Background: Soft Tissue Sarcoma is one of the rare cancers that increased in number in the last few years, but information about soft tissue sarcoma patients was still limited, especially in West Java, Indonesia. This study aimed to find out the patient profile and the histopathological cell distribution of soft tissue sarcoma patients who undergo radiotherapy.
Methods: The study design was retrospective descriptive quantitative with the total sampling method. This study was done by observing all patients’ medical records registered from January 1, 2018, until December 31, 2019, in the Hospital-Based Cancer Registry of Radiology Department of Dr. Hasan Sadikin General Hospital Bandung, with the inclusion criterion of patients diagnosed with soft tissue sarcoma.
Results: A total of 5% (n = 75) from 1,388 cases registered were soft tissue sarcoma. The most common patient profile was female (57.3%) and age group 45–54 years (21.3%). The chief complaint was dominated by a painless mass (56.0%) at the lower limb (37.8%) with the most frequent cell of fibrosarcoma (17.3%), the most intention of the radiotherapy of curative adjuvant (78.7%).
Conclusions: The number of soft tissue sarcoma is small compared to other malignancies. It is more common in women, the most age group is from 45 to 54 years with the median of 47 years old, ranging from 9 to 90 years, it tends to occur in the lower limb with a chief complaint of a painless mass, and the most frequent cell is fibrosarcoma. The common treatment combination is surgery with radiotherapy
Yang Z, Zheng R, Zhang S, et al. Incidence, distribution of histological subtypes and primary sites of soft tissue sarcoma in China. Cancer Biol Med. 2019;16(3):565–74.
Fabiano S, Contiero P, Barigelletti G, et al. Epidemiology of Soft Tissue Sarcoma and Bone Sarcoma in Italy: Analysis of Data from 15 Population-Based Cancer Registries. Sarcoma. 2020;2020:1–10.
Brennan MF, Antonescu CR, Maki RG. Management of soft tissue Sarcoma. second. Vol. 9781461450, Management of Soft Tissue Sarcoma. Switzerland: Springer; 2016. 1–380 p.
Washington CM, Leaver D. Principles and Practice of Radiation Therapy. 4th ed. Vol. 15, Radiography. Elsevier Ltd; 2017. 357 p.
Kollár A, Rothermundt C, Klenke F, et al. Incidence, mortality, and survival trends of soft tissue and bone sarcoma in Switzerland between 1996 and 2015. Cancer Epidemiol. 2019;63:101596.
Arfiana W, Laode B, Fidiawati WA. The Distribution Of Soft Tissue Sarcoma Based On Histopathology’s Check-in Pekanbaru’s Hospital Between 2009-2013. Jom FK. 2016;3(1):1–21.
Bhatt N, Deady S, Gillis A, et al. Epidemiological study of soft-tissue sarcomas in Ireland. Cancer Med. 2016;5(1):129–35.
Liu YL, Lo WC, Chiang CJ, et al. Incidence of cancer in children aged 0–14 years in Taiwan, 1996–2010. Cancer Epidemiol. 2015;39(1):21–8.
Stiller CA, Botta L, Brewster DH, et al. Survival of adults with cancers of bone or soft tissue in Europe—Report from the EUROCARE-5 study. Cancer Epidemiol. 2018;56:146–53.
Goldblum JR, Folpe AL, Weiss S w. Soft Tissue Tumors. 7th ed. Philadelphia: Elsevier; 2020. 1242 p.
Fioretti F, Tavani A, Gallus S, et al. Menstrual and reproductive factors and risk of soft tissue sarcomas. Cancer. 2000;88(4):786–9.
Folpe AL. Fibrosarcoma: a review and update. Histopathology. 2014;64(1):12–25.
Sajjad M, Ahmad F, Khan ZA, Shah H. Histopathological Pattern of Soft Tissues Tumors And Tumour Like Lesions In The Pathology Department Of Lady Reading Hospital Peshawar, Pakistan. J Ayub Med Coll Abbottabad. 2016;28(3):514–7.
Bessen T, Caughey GE, Shakib S, et al. A population-based study of soft tissue sarcoma incidence and survival in Australia: An analysis of 26,970 cases. Cancer Epidemiol. 2019;63:101590.
American Cancer Society. Cancer Facts & Figures 2020. [Internet]. 2020 [cited 2020 Jun 15]. Available from: https://www.cancer.org/cancer/soft-tissue-sarcoma/about/key-statistics.html
Ward E, DeSantis C, Robbins A, Kohler B JA. Childhood and adolescent cancer statistic. A Cancer J Clin. 2014;64(2):83–103.
Augsburger D, Nelson PJ, Kalinski T, et al. Current diagnostics and treatment of fibrosarcoma -perspectives for future therapeutic targets and strategies. Oncotarget. 2017;8(61):104638–53.
Frenkel M. Refusing Treatment. Oncologist. 2013;18(5):634–6.
Hansen H, Skovhus Thomsen M. EP-1851: Why is planned palliative radiotherapy often cancelled? A retrospective exploratory study. Radiother Oncol. 2017;123:S1012.
Grover S, Xu MJ, Yeager A, et al. A systematic review of radiotherapy capacity in low- and middle-income countries. Front Oncol. 2014;4:380.
Yap ML, Zubizarreta E, Bray F, et al. Global Access to Radiotherapy Services: Have We Made Progress During the Past Decade?. J Glob Oncol. 2016;2(4):207–15.
Cho HS, Lee YS, Lee SG, et al. Reasons for Surgery Cancellation in a General Hospital: A 10-year Study. Int J Environ Res Public Health. 2018;16(1).
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