Characteristics of Breast Cancer in Young Female Patients in Dr. Mohammad Hoesin General Hospital Palembang

Atik Diah Mutiara Ningsih, Nur Qodir, Ahmat Umar, Mulawan Umar, Puji Rizki Suryani, Citra Dewi

Abstract


Background: Breast cancer has had the highest mortality and morbidity globally in recent years. Breast cancer in young women presents with biological characteristics of more aggressive cancer, generally detected at advanced stage and a poorer prognosis. This study aimed to determine the characteristics of the incidence of breast cancer in young female patients at Dr. Mohammad Hoesin General Hospital Palembang in 2019–2020.

Methods: This study is descriptive observational study conducted in October–November 2021. After having ethical approval from the Institutional Review Committee, research data were obtained from the medical records of young female patients diagnosed with breast cancer from January 1, 2019 to December 31, 2020. Samples were collected by using total sampling with the patient’s young age limit of fewer than 40 years.

Results: The incidence of breast cancer was 20.9% (169 patients). The number of samples in this study was 120. Sociodemographic characteristics include the age range of 35–39 years around 63.3% (76 people), the highest education level of senior high school around 35% (42 people), not working around 73.3% (88 people), and living in the Palembang City area around 47.5% (57 people). Clinicopathological characteristics include the stage at the first diagnosis of stage IIIB about 46.7% (56 people), luminal B clinical subtype about 60% (72 people), and most histopathological type of invasive carcinoma of no special type about 88.3% (106 people).

Conclusions: The incidence of breast cancer in young women is less than in older women but has worse cancer characteristics


Keywords


breast cancer, characteristic, women, young age

Full Text: View | Download

DOI: 10.33371/ijoc.v16i4.907

Article Metrics

Abstract View: 431,
PDF Download: 221
             

References


Feng Y, Spezia M, Huang S, et al. Breast Cancer Development And Progression: Risk Factors, Cancer Stem Cells, Signaling Pathways, Genomics, And Molecular Pathogenesis. Genes Dis. 2018;5(2):77–106.

Britt KL, Cuzick J, Phillips KA. Key Steps For Effective Breast Cancer Prevention. Nat Rev Cancer. 2020;20(8):417–36.

Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71(3):209–49.

Pelima, Tri Cita. Faktor yang Mempengaruhi Keterlambatan Diagnosis Awal Pasien Kanker Payudara Tri Cita Pelima. Jurnal Penelitian Kesehatan Suara Forikes. 2021;12(2502–7778):258–60.

Anastasiadi Z, Lianos GD, Ignatiadou E, et al. Breast Cancer In Young Women : An Overview. Updates Surgeon. 2017;69(3):313–7.

Awaliah RP, Dewi C, Rasyid RSP. Karakteristik Klinikopatologik serta Hubungan Derajat Keganasan dengan Subtipe Molekular Luminal B pada Pasien Karsinoma Payudara di RSUP Mohammad Hoesin Palembang Tahun 2014-2016. 2022;31(1):351–8.

American Cancer Society. American Cancer Society. Cancer Facts & Figures 2021. Atlanta: American Cancer Society; 2021. 2021. p. 1–72.

Partini PDO, Niryana IW, Adiputra PAT. Karakteristik kanker payudara usia muda di Subbagian Bedah Onkologi Rumah Sakit Umum Pusat Sanglah tahun 2014-2016. Intisari Sains Medis. 2018 Apr 30;9(1).

Pratama NMW, Wetan NGAAMY, Widiana IK. Faktor yang Mempengaruhi Keterlambatan Pengobatan Kanker Payudara: Sebuah Tinjauan Sistematik. Intisari Sains Media. 2021;12(1):346–55.

Maria IL, Sainal AA, Nyorong M. Risiko Gaya Hidup Terhadap Kejadian Kanker Payudara Pada Wanita. Media Kesehatan Masyarakat Indonesia. 2017;13(2):157.

Nurhayati. Faktor-faktor Risiko Yang Berhubungan Dengan Kejadian Kanker Payudara Di Rumah Sakit Umum Daerah Kota Padangsidimpuan. J War Ed 56. 2018;(April).

Momenimovahed Z, Salehiniya H. Epidemiological Characteristics Of And Risk Factors For Breast Cancer In The World. Breast Cancer Targets Ther. 2019;11:151–64.

Hortobagyi GN, Conolly JL, D’Orsi CJ, et al. Breast Cancer Staging System: AJCC Cancer Staging Manual, Eighth Edition. American Collegium Surgeon. 2017;589–636.

Amin MB, Greene FL, Edge SB, et al. The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population-based to a more "personalized" approach to cancer staging. CA Cancer J Clin. 2017 Mar;67(2):93-99.

Eiriz IF, Vaz Batista M, Cruz Tomás T, et al. Breast Cancer In Very Young Women—A Multicenter 10-Year Experience. ESMO Open. 2021;6(1):100029.

Paramita S, Raharjo EN, Niasari M, et al. Luminal B Is The Most Common Intrinsic Molecular Subtypes Of Invasive Ductal Breast Carcinoma Patients In East Kalimantan, Indonesia. Asian Pacific J Cancer Prev. 2019;20(8):2247–52.

Zhang L, Huang Y, Feng Z, et al. Comparison Of Breast Cancer Risk Factors Among Molecular Subtypes: A Case-Only Study. Cancer Med. 2019;8(4):1882–92.

Weiss A, Chavez-Macgregor M, Lichtensztajn DY, et al. Validation Study of the American Joint Committee on Cancer Eighth Edition Prognostic Stage Compared With the Anatomic Stage in Breast Cancer Supplemental content. JAMA Oncol. 2018;4(2):203–9.

West AKV, Wullkopf L, Christensen A, et al. Dynamics Of Cancerous Tissue Correlates With Invasiveness. Sci Rep. 2017;7(November 2016):1–11.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2022 Indonesian Journal of Cancer

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.