Resection of Anaplastic Meningioma via Combined Craniofacial Approach

Yosafat Kurniawan Sugiarto, Arwinder Singh, Muhammad Firdaus, Oskar Ady Widarta, Farilaila Rayhani

Abstract


Introduction: Meningiomas are common and mostly benign intracranial tumors but may show a histological progression to malignancy. The mechanism of malignant transformation remains unclear. Malignant meningiomas usually bear a high recurrence rate and unfavorable prognosis; hence, multiple surgical resections are required for the treatment

Case Presentation: A 41-year-old woman with a prior history of craniotomy at another center six years ago with Meningioma Grade 1 presented to our institution with new neurological symptoms. The magnetic resonance image demonstrated a large frontal base mass that extended to the nasal cavity with diffuse contrast enhancement and extensive surrounding edema. A craniofacial approach combined with a bifrontal approach was performed in multistage tumor resection. The tumor and the infiltrated dura were radically removed. The histopathology demonstrated an Anaplastic Meningioma. The patient also underwent radiation therapy.

Conclusion:  Treatment of recurrent meningioma with anaplastic histology remains challenging because recurrence rates remain high with a poor prognosis.


Keywords


anaplastic meningioma, craniofacial approach

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DOI: 10.33371/ijoc.v16i4.910

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